C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/22 (2006.01) A61K 31/195 (2006.01) A61K 31/41 (2006.01) A61K 31/66 (2006.01) C07C 229/26 (2006.01) C07C 271/12 (2006.01) C07C 271/22 (2006.01) C07C 275/16 (2006.01) C07C 311/06 (2006.01) C07C 335/08 (2006.01) C07D 257/04 (2006.01) C07D 295/15 (2006.01) C07D 453/02 (2006.01) C07F 9/38 (2006.01) C07F 9/54 (2006.01) C07F 9/58 (2006.01) C07F 9/6561 (2006.01)
Patent
CA 2329930
Compounds of formula (I) wherein the groups are as defined in the description are disclosed. The compounds of formula (I) are endowed with reversible inhibiting activity of carnitine palmitoyl-transferase and are useful in the preparation of medicaments useful in the pathologies related to a hyperactivity of carnitine palmitoyl-transferase, such as hyperglycemia, diabetes and pathologies related thereto, heart failure, ischemia.
Composés représentés par la formule (I) dans laquelle les groupes correspondent à leur définition dans le descriptif. Ces composés exercent une activité d'inhibition réversible de carnitine palmityl-transférase et sont utiles pour préparer des médicaments servant à traiter des pathologies apparentées à une hyperactivité de carnitine palmityl-transférase, telles que l'hyperglycémie, le diabète et des maladies associées, l'insuffisance cardiaque ou l'ischémie.
Arduini Arduino
Chiodi Piero
de Angelis Francesco
Giannessi Fabio
Marzi Mauro
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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