Compounds having selectivity for retinoid x receptors

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 213/80 (2006.01) A61K 31/166 (2006.01) A61K 31/192 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) C07C 63/06 (2006.01) C07C 63/49 (2006.01) C07C 233/75 (2006.01) C07D 213/79 (2006.01) C07D 257/10 (2006.01) C07K 14/705 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2133587

Compounds, compositions, and method for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, and pyrrole derivatives. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.

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