C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) C07K 14/59 (2006.01) G01N 33/566 (2006.01) G01N 33/76 (2006.01)
Patent
CA 2166385
Disclosed are compounds having antigenic binding affinity with antibodies directed against human chorionic gonadotropin. The compounds typically include or consist of an oligopeptide with thc sequence: AA1' AA2' AA3' AA4' AA5' AA6', wherein AA1' is Gly, Asn, Ser, Phe, Arg, Leu, or Lys; AA2' is Pro, Trp, Ala, Va or Glu; AA3' is Arg, Gln, Ile, Met, Va? Thr, Ser, Gly, or Phe; AA4' is Tyr, Glu, Leu, Phe, Pro, or Thr, AA5' is Asp, Asn, Leu, Met, Va? Tyr, Ser, Ile, Ala, Gly, or Phe; and AA6' is Phe, Trp, Ala, Thr, Arg, Asp, or Val.
L'invention concerne des composés qui ont une affinité antigénique avec des anticorps opposés à la gonadotrophine chorionique. En général, ces composés contiennent ou consistent en un oligopeptide dont la séquence est la suivante: AA1' AA2' AA3' AA4' AA5' AA6'; AA1' étant l'un des éléments suivants: Gly, Asn, Ser, Phe, Arg, Leu ou Lys; AA2' étant l'un des éléments suivants: Pro, Trp, Ala, Val ou Glu; AA3' étant l'un des éléments suivants: Arg, Gln, Ile, Met, Val, Thr, Ser, Gry ou Phe; AA4' étant l'un des éléments suivants: Tyr, Glu, Leu, Phe, Pro ou Thr; AA5' étant l'un des éléments suivants: Asp, Asn, Leu, Met, Val, Tyr, Ser, Ile, Ala, Gly ou Phe; et AA6' étant l'un des éléments suivants: Phe, Trp, Ala, Thr, Arg, Asp ou Val.
Oyen Wiggs Green & Mutala Llp
University Of Utah Research Foundation
LandOfFree
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