C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
402/364, 167/5
C08G 73/06 (2006.01) A01N 43/40 (2006.01) A61K 31/745 (2006.01) A61K 31/785 (2006.01) A61L 2/18 (2006.01) A61L 12/14 (2006.01) C08F 226/04 (2006.01) C08L 79/04 (2006.01)
Patent
CA 1142297
ABSTRACT Watersoluble terpolymers based on three monomer units all of formula: (or possibly the Image 5-membered ring analogue) wherein the N-substituents are respectively (A)low-low e.g. dimethyl (B)low-medium e.g. methyloctyl and (C)low-higher e.g. methyllauryl or methylcetyl, in molecular size; B:C being usually 5:1 to 0.333:1 (preferably 2:1 to 1:1) in weight ratio, and species less surprisingly effective sterilizing activity e.g. against Candida while (a) not accumulating in soft contact lenses, whereby they can be used as an overnight nonirritant aqueous sterilant solution at concentrations below 0.1 weight percent e.g. 0.05 or less and (b) not penetrating skin or like membrane whereby aqueous formulations can be uses as topical disinfectants without systemic side-effects.
326426
Andrews John K.
Howes John G.b.
Selway Rupert A.
Marks & Clerk
Smith & Nephew Pharmaceuticals Limited
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