Compounds of the plasminogen type and method for obtaining...

Details Compounds of the plasminogen type and method for obtaining... Compounds of the plasminogen type and method for obtaining...

A - Human Necessities

61

K

167/113

A61K 35/50 (2006.01)

Patent

CA 1046406

IN THE PATENT OFFICE PATENT APPLICATION entitled " COMPOUNDS OF THE PLASMINOGEN TYPE AND METHOD FOR OBTAINING SUCH COMPOUNDS FROM PLACENTAL PULP " in the names of LORMEAU Jean-Claude GOULAY Jean and VAIREL Edmond ABSTRACT OF THE DISCLOSURE The placental pulps notably of human origin are separated from the placental blood, which is removed, and the pulps are macerated in the midst of a solution at a pH comprised between 5 and 10, e.g. isotonic NaCl solution, preferably at neutral pH, in the presence of an amino-acid inhibitor of plasminogen activation, at a molar concentration comprised between about 0.001 and 0,1 M, preferably of the order of 0.035 M. The pulps are removed and the solution containing the compounds of the plasminogen type is recovered. Preferred inhibitors are L-lysin, epsilon aminocaproic acid, and trans-4 amino- methyl cyclohexane carboxylic acid.

215976

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