Compounds, preparation and use for transferring nucleic...

Details Compounds, preparation and use for transferring nucleic... Compounds, preparation and use for transferring nucleic...

C - Chemistry, Metallurgy

07

C

C07C 279/12 (2006.01) A61K 9/127 (2006.01) A61K 48/00 (2006.01) C07C 257/14 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2290664

The invention concerns novel compounds for transferring nucleic acids into cells. Said novel compounds are more particularly related to the lipopolyamine family, and comprise amidine functions. Said compounds are useful for transferring nucleic acids of interest into various cellular types, in vitro, in vivo, or ex vivo.

La présente invention concerne de nouveaux composés de transfert d'acides nucléiques dans les cellules. Ces nouveaux composés, de formule générale (I), sont plus particulièrement apparentés à la famille des lipopolyamines, et comportent des fonctions amidines. Ces composés sont utilisables pour transférer des acides nucléiques d'intérêt dans différents types cellulaires, aussi bien in vitro que in vivo ou ex vivo. (voir formule I)

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