Compounds that are erk inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 403/14 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2714479

Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydopyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1Ø

La présente invention concerne des inhibiteurs de la voie ERK de formule 1.0 : et leurs sels pharmaceutiquement acceptables, ainsi que leurs solvates. Q est un cycle tétrahydropyridinyle. Tous les autres substituants sont tels que définis dans les présentes. L'invention concerne également des procédés de traitement du cancer au moyen desdits composés de formule 1Ø

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