C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/10 (2006.01) A61K 31/4168 (2006.01) A61K 31/4196 (2006.01) C07D 249/12 (2006.01)
Patent
CA 2682665
The present invention relates to compounds according to formulae (IA) to (ID) and compositions that inhibit the activity of Hsp90. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a compound of the invention, or a composition comprising such a compound.
La présente invention concerne des composés et des compositions qui inhibent l'activité de Hsp90. L'invention concerne également des procédés d'inhibition de l'activité de Hsp90 chez un sujet le nécessitant et des procédés de prévention ou de traitement de troubles hyperprolifératifs, tels que le cancer, chez un sujet le nécessitant. Ces procédés comprennent l'administration au sujet d'un composé selon l'invention ou d'une composition qui comprend un tel composé.
Du Zhenjian
Foley Kevin
Lee Chi-Wan
Przewloka Teresa
Qin Shuzhen
Gowling Lafleur Henderson Llp
Synta Pharmaceuticals Corp.
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