Compounds that modulate intracellular calcium

Details Compounds that modulate intracellular calcium Compounds that modulate intracellular calcium

C - Chemistry, Metallurgy

07

D

C07D 409/02 (2006.01) A61K 31/415 (2006.01) A61P 19/00 (2006.01) A61P 19/02 (2006.01) A61P 25/28 (2006.01) C07D 231/56 (2006.01) C07D 277/60 (2006.01) C07D 413/12 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2734500

Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.

L'invention porte sur des composés et des compositions pharmaceutiques contenant de tels composés, qui modulent l'activité de canaux calciques capacitifs (SOC). L'invention porte également sur des procédés d'utilisation de tels modulateurs de canaux SOC, seuls ou en combinaison avec d'autres composés, pour traiter des maladies ou des états pathologiques qui pourraient bénéficier d'une inhibition de l'activité des canaux SOC.

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