C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/192 (2006.01) A61K 31/352 (2006.01) A61K 31/381 (2006.01) A61P 3/00 (2006.01) A61P 9/10 (2006.01) C07C 62/10 (2006.01) C07C 323/20 (2006.01) C07C 323/21 (2006.01) C07D 213/34 (2006.01) C07D 307/79 (2006.01) C07D 311/58 (2006.01) C07D 333/60 (2006.01) C07D 405/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2522118
This invention relates to compounds that alter PPAR activity. The invention also relates to pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing dyslipidemia, hypercholesterolemia, obesity, hyperglycemia, atherosclerosis, hypertriglyceridemia and hyperinsulinemia in a mammal. The present invention also relates to methods for making the disclosed compounds.
L'invention concerne des composés modifiant l'activité des récepteurs PPAR. Elle concerne également des sels pharmaceutiquement acceptables de ces composés, des compositions pharmaceutiquement acceptables renfermant ces composés ou leurs sels, ainsi que des procédés pour les utiliser comme agents thérapeutiques en vue de traiter ou de prévenir la dyslipidémie, l'hypercholestérolémie, l'obésité, l'hyperglycémie, l'athérosclérose, l'hypertriglycéridémie et l'hyperinsulinémie chez un mammifère. La présente invention concerne également des procédés pour fabriquer les composés décrits.
Bratton Larry Don
Cheng Xue-Min
Erasga Noe Ouane
Filzen Gary Frederick
Geyer Andrew George
Smart & Biggar
Warner-Lambert Company Llc
LandOfFree
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