Compounds useful as phosphotyrosine mimics

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/27 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2363689

New uses are disclosed for compositions containing compounds of formula (I) wherein A, B, C, G, Q and R are defined herein. The compositions inhibit the binding of tyrosine kinase-dependent regulatory proteins to their native phosphotyrosine-containing ligands or receptors. Also disclosed are methods for preparing the compounds of formula (I).

La présente invention concerne de nouvelles utilisations de compositions contenant des composés de la formule (I) ci-dessous, dans laquelle A, B, C, G, Q et R sont définis ici. Ces compositions inhibent la liaison des protéines régulatrices dépendantes de la tyrosine-kinase avec leurs ligands ou récepteurs natifs contenant la phosphotyrosine. En outre, cette invention concerne des procédés de préparation des composés de la formule (I).

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