C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/20 (2006.01) A61K 31/325 (2006.01) A61K 31/34 (2006.01) A61K 31/35 (2006.01) A61K 31/435 (2006.01) A61K 31/5375 (2006.01) A61P 37/00 (2006.01) C07C 271/64 (2006.01) C07C 323/60 (2006.01) C07D 211/22 (2006.01) C07D 213/30 (2006.01) C07D 213/57 (2006.01) C07D 239/80 (2006.01) C07D 263/32 (2006.01) C07D 275/06 (2006.01) C07D 277/30 (2006.01) C07D 295/215 (2006.01) C07D 307/12 (2006.01) C07D 307/54 (2006.01) C07D 309/12 (2006.01) C07D 333/24 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01)
Patent
CA 2459825
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (Ia) and (Ib) where R1, R2, R3, R4, R5, R6, R8, R9 and X aredefined herein. The compoundsare useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds.
L'invention concerne de nouveaux composés inhibiteurs réversibles de cathépsines S, K, F, L et B des formules (Ia) et (Ib) dans lesquelles R<sb>1</sb>, R<sb>2</sb>, R<sb>3</sb>, R<sb>4</sb>, R<sb>5</sb>, R<sb>6</sb>, R<sb>8</sb>, R<sb>9</sb> et X sont tels que définis dans le descriptif. Les composés sont utiles pour le traitement de maladies auto-immunes et d'autres maladies. Font également l'objet de cette invention des procédés de fabrication desdits nouveaux composés.
Bekkali Younes
Hickey Eugene R.
Liu Weimin
Patel Usha R.
Spero Denice Mary
Boehringer Ingelheim Pharmaceuticals Inc.
Fetherstonhaugh & Co.
LandOfFree
Compounds useful as reversible inhibitors of cysteine proteases does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds useful as reversible inhibitors of cysteine proteases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds useful as reversible inhibitors of cysteine proteases will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1666280