C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 255/46 (2006.01) A61K 31/12 (2006.01) A61K 31/275 (2006.01) C07C 43/315 (2006.01) C07C 45/44 (2006.01) C07C 45/51 (2006.01) C07C 45/71 (2006.01) C07C 47/47 (2006.01) C07C 47/575 (2006.01) C07C 49/577 (2006.01) C07C 49/753 (2006.01) C07C 49/757 (2006.01) C07C 217/48 (2006.01) C07C 233/56 (2006.01) C07C 235/40 (2006.01) C07C 235/82 (2006.01) C07C 255/64 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2133337
Novel cyclohexanes of formulas (I) and (II) are described herein. They inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production; these compounds are also useful in the mediation or inhibition of enzymatic or catalytic activity of phosphodiesterase IV.
Bender Paul Elliot
Christensen Siegfried Benjamin IV
Forster Cornelia Jutta
Glaxosmithkline Llc
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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