C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61P 25/00 (2006.01) C07D 401/10 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/10 (2006.01) C07D 417/10 (2006.01)
Patent
CA 2646585
Compounds of formula (I) and salts and solvates are provided: formula (I). Processes for preparation, pharmaceutical compositions, and uses thereof as a medicament, for example in the treatment of a disease or condition mediated by a reduction or imbalance in glutamate receptor function, such as schizophrenia or cognition impairment, are also disclosed.
La présente invention concerne des composés répondant à la formule (I) et leurs sels et solvates : voir la formule (I). L'invention concerne également des procédés de préparation, des compositions pharmaceutiques, et leurs utilisations en tant que médicament, par exemple dans le traitement d'une maladie ou d'une pathologie médiée par une réduction ou un déséquilibre de la fonction du récepteur du glutamate, telle que la schizophrénie ou une déficience intellectuelle.
Bradley Daniel Marcus
Chan Wai Ngor
Harrison Stephen
Thatcher Robert
Thewlis Kevin Michael
Glaxo Group Limited
Gowling Lafleur Henderson Llp
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