Compounds with a nitrogen-containing heterocyclic nucleus,...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) C07C 233/83 (2006.01) C07D 213/61 (2006.01) C07D 213/80 (2006.01) C07D 239/30 (2006.01) C07D 239/36 (2006.01) C07D 491/10 (2006.01)

Patent

CA 1254200

IN THE CANADIAN PATENT & TRADEMARK OFFICE PATENT APPLICATION entitled: New compounds with a nitrogen-containing heterocyclic nucleus, their preparation and drugs in which they are present. in the names of: Kathleen BIZIERE Jean-Pierre CHAMBON André HALLOT Assignee: Société anonyme styled: SANOFI ABSTRACT OF THE DISCLOSURE The invention relates to compounds with a nitrogen-containing heterocyclic nucleus, of the general formula: (I) Image in which: - Ar represents a group Image or a naphthyl group optionally substituted by a halogen, - A represents a heterocyclic nucleus chosen from the group consisting of the pyridine, pyrimidine and triazine nuclei, and - X and Y, taken separately, denote a hydrogen atom in one case and a group OR3 (hydroxyl, carbamate or ester) in the other. The invention also relates to a process for the preparation of these compounds and their applica- tion as drugs acting on the central nervous system.

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