Compounds with ergoline skeleton and a process for the...

Details Compounds with ergoline skeleton and a process for the... Compounds with ergoline skeleton and a process for the...

C - Chemistry, Metallurgy

07

D

260/206

C07D 457/06 (2006.01) C07D 457/02 (2006.01)

Patent

CA 1051878

ABSTRACT OF THE DISCLOSURE New compounds of the general formula (I) Image (I) wherein R stands for hydrogen or methyl or methyl group, x y stands for a group of the formula Image or Image , and R1 stands for a group of the formula (III), (IV) or (V) Image (III) Image (IV) Image (V) wherein n is an integer from 4 to 10, are prepared by acylating a compound of the general formula (II), - 2 - Image (II) wherein R and Image each have the same meanings as defined above, and R2 stands for a group of the formula (VI), (VII) or (VIII), (VI) Image (VII) Image Image (VIII) with a C6-12 carboxylic acid or a C6-12 carboxylic acid halide, The new compounds of the general formula (I) and their acid addition salts can be used as antidepressants and antiserotonine agents with prolonged effects.

227849

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