C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/065 (2006.01) A61K 31/16 (2006.01) A61K 31/40 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07C 237/22 (2006.01) C07D 207/09 (2006.01) C07D 271/06 (2006.01) C07D 333/24 (2006.01) C07D 413/12 (2006.01) C07K 5/03 (2006.01) C07K 5/06 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2239711
Compounds of peptide mimetic nature having general formula (I), wherein a and b are independently 1 or 2, R1 and R2 are independently H or C1-6alkyl, G and J are independently, inter alia, aromats, and D and E are independently several different groups, are growth hormone secretagogous with improved bioavailability.
L'invention concerne un peptide de nature mimétique ayant la formule générale (I). Dans cette formule, a et b sont, d'une manière indépendante 1 ou 2, R?1¿ et R?2¿ sont, d'une manière indépendante H ou C¿1-6? alkyle, G et J sont, d'une manière indépendante, entre autres, des groupes aromatiques et D et E sont, d'une manière indépendante, plusieurs groupes différents. Ces peptides favorisent la sécrétion de l'hormone de croissance et améliorent sa biodisponibilité.
Ankersen Michael
Hansen Thomas Kruse
Lau Jesper
Lundt Behrend Friedrich
Madsen Kjeld
Mccarthy Tetrault Llp
Novo Nordisk A/s
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