A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/495 (2006.01) A61P 9/00 (2006.01) C07D 237/04 (2006.01) C07D 401/04 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2588949
This invention provides compounds that possess inhibitory activity against .beta.-adrenergic receptors and phosphodiesterases, including phosphodiesterase 3 (PDE3). This invention further provides pharmaceutical compositions comprising such compounds; methods of using such compounds for treating cardiovascular disease, stroke, epilepsy, ophthalmic disorder or migraine; and methods of preparing pharmaceutical compositions and compounds that possess inhibitory activity against .beta.-adrenergic receptors and PDE.
Cette invention concerne des composés qui présentent une activité inhibitrice contre des récepteurs .beta.-adrénergiques et des phosphodiestérases, y compris la phosphodiestérase 3 (PDE3). Cette invention concerne également des compositions pharmaceutiques renfermant ces composés, des procédés utilisant ces composés pour traiter une maladie cardiovasculaire, un accident vasculaire cérébral, l'épilepsie, un trouble ophtalmique ou la migraine, ainsi que des procédés de préparation de compositions pharmaceutiques et de composés qui présentent une activité inhibitrice contre des récepteurs .beta.-adrénergiques et la PDE.
Klenke Burkhard
Mazhari Reza
Suzdak Peter D.
Taylor Malcolm George
Artesian Therapeutics Inc.
Mccarthy Tetrault Llp
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