A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/22 (2006.01) A61K 9/20 (2006.01) A61K 31/192 (2006.01) A61K 47/36 (2006.01)
Patent
CA 2339190
A solid sustained release pharmaceutical composition comprising a compressed mixture of a pharmacologically active ingredient and a sustained release carrier comprising xanthan gum characterised in that the xanthan gum is capable of dissolving in water at a concentration of 1 part by weight xanthan gum to 100 parts by weight water to form a solution having a transmittance (600 nm) of greater than 50 %. The clarified xanthan gum has an improved reproducibility in drug dissolution.
La présente invention une composition pharmaceutique solide à libération lente comprenant un mélange comprimé d'un ingrédient pharmacologiquement actif et d'un support à libération lente constitué de gomme xanthane, caractérisée en ce que la gomme xanthane est capable de se dissoudre dans l'eau à une concentration de 1 partie de gomme xanthane en poids dans 100 parties d'eau en poids afin de former une solution qui présente une transmittance (600 nm) supérieure à 50 %. La gomme xanthane clarifiée présente une reproductibilité améliorée concernant la dissolution de médicaments.
Mccarthy Tetrault Llp
Reckitt Benckiser Healthcare (uk) Limited
The Boots Company Plc
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