Compressed dry-granulation desogestrel tablets

Details Compressed dry-granulation desogestrel tablets Compressed dry-granulation desogestrel tablets

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61J 3/06 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2224269

The invention concerns compressed dry-granulation tablets or granules comprising desogestrel obtainable by roller compaction or by slugging, which can be prepared by a method of production, whereby desogestrel, optionally together with other active compounds and/or excipients, in a first step of the process is compressed by applying elevated pressure, and thereafter in a second step is crushed into particles, after which in a third step the particles may be processed into tablets or filled into capsules, using methods known in the art.

L'invention se rapporte à des tablettes ou granules compressées de granulation sèche comprenant du désogestrel obtenu par compactage au rouleau, ou par production de granules, pouvant être préparées par un procédé de production. Dans ledit procédé, le désogestrel, éventuellement avec d'autres éléments actifs et/ou excipients, est tout d'abord compressé par application d'une pression élevée, et ensuite, dans un deuxième temps, écrasé en particules. Après quoi, dans une troisième étape les particules peuvent être transformées en tablettes ou mises en capsules, selon les procédés connus de l'état de la technique.

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