Compressible and free-flow co-agglomerates of mannitol and...

Details Compressible and free-flow co-agglomerates of mannitol and... Compressible and free-flow co-agglomerates of mannitol and...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2755992

The invention relates to co-agglomerates of crystalline mannitol and granular starch, characterised in that they have a compressibility, as determined according to a test A, higher than 120 N, and preferably of 200 to 450 N, and a flow time, as determined according to a test B, of 3 to 15 seconds, and preferably of 4 to 8 seconds.

L'invention a pour objet des coagglomérats de mannitol cristallin et d'amidon granulaire, caractérisé en ce qu'ils présentent une comprimabilité, déterminée selon un test A, supérieure à 120 N, de préférence comprise entre 200 et 450 N, et une note d'écoulement, déterminée selon un test B, comprise entre 3 et 15 secondes, de préférence comprise entre 4 et 8 secondes.

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