Compression-coated tablets and manufacture thereof

Details Compression-coated tablets and manufacture thereof Compression-coated tablets and manufacture thereof

A - Human Necessities

61

K

A61K 9/28 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2555774

Tablets for the treatment of migraine comprise a core, containing the active agent sumatriptan or a pharmaceutically-acceptable salt or ester thereof, and a mantle, free of sumatriptan. Tablets are prepared by compressing mantle components, free of the active agent, around a partially-compressed, active- containing core.

La présente invention se rapporte à des comprimés destinés à traiter la migraine, qui comprennent un noyau contenant l'agent actif sumatriptan ou un sel pharmaceutiquement acceptable ou un ester dudit agent, et un enrobage exempt de sumatriptan. Un procédé de préparation des comprimés selon l'invention consiste à comprimer des éléments d'enrobage, exempts de l'agent actif, autour d'un noyau partiellement comprimé contenant l'agent actif.

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