Compsitions containing alkannin derivatives for treating...

A - Human Necessities – 61 – K

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A61K 31/12 (2006.01) A61K 31/215 (2006.01) A61K 31/22 (2006.01) C07C 46/10 (2006.01) C07C 50/32 (2006.01)

Patent

CA 1118355

COMPOSITIONS CONTAINING ALKANNIN DERIVATIVES FOR TREATING SKIN DISORDERS Abstract of the Disclosure The present invention provides a composition suitable for external application against skin disorders, e.g. Ulcus cruris, and having as its active ingredient a compound of the general formula Image wherein Y is hydrogen or -OX where X represents hydrogen, a carboxylic acid residue, or a derivative of a carboxylic acid residue, and R1 and R2 are alkyl groups. The compound in which X is the acetyl ester of the 3-methyl-3-hydroxy-butanecarboxylic acid residue is a novel compound which is exceptionally active. The active compounds can be extracted from plants in which they occur at a temperature not exceeding 80°C. in an inert atmosphere in the substantial absence of light and oxygen.

294371

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