Computational selection of probes for localizing chromosome...

G - Physics – 01 – N

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G01N 33/48 (2006.01)

Patent

CA 2566395

The present invention provides a novel method for selecting genomic hybridization probes. The method generally includes the step of selecting a genomic interval of interest, identifying at least one potential hybridization probe that has known coordinates within the interval of interest, applying a numerical method to sample the identified probe(s) based on its genome coordinates, and selecting a probe based on the result of the numerical method.

L'invention concerne un nouveau procédé de sélection de sondes d'hybridation génomique. De manière générale, ce procédé consiste à sélectionner un intervalle génomique désiré, à identifier au moins une sonde d'hybridation potentielle présentant des coordonnées connues se situant dans l'intervalle désiré, et à appliquer un procédé numérique permettant d'échantillonner la ou les sonde(s) identifiée(s) en fonction de ses/leurs coordonnées génomiques, et à sélectionner une sonde conformément au résultat de ce procédé numérique.

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