Computational system for modelling protein expression in an...

Details Computational system for modelling protein expression in an... Computational system for modelling protein expression in an...

G - Physics

06

F

G06F 17/00 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2412375

A computational model of an organ is disclosed along with a process for assessing the microscopic and whole organ impact of genetic differences that occur in single cells comprising the organ. The genetic differences in the model are based on changes on protein function or distribution associated with genetic mutations, gender, disease or allele based variations in the pattern of gene expression.

L'invention concerne un modèle informatique d'un organe ainsi qu'un procédé permettant d'évaluer l'impact des différences génétiques, qui se produisent dans les cellules simples dont se compose l'organe, au niveau microscopique ainsi qu'au niveau de l'organe entier. Les différences génétiques dans le modèle reposent sur des changements de fonction ou de distribution de protéines, associés aux mutations génétiques, au sexe, à la maladie ou aux variations occasionnées par des allèles dans la configuration de l'expression des gènes.

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