Computer systems and methods for subdividing a complex...

Details Computer systems and methods for subdividing a complex... Computer systems and methods for subdividing a complex...

G - Physics

06

F

G06F 19/00 (2006.01) C12N 15/00 (2006.01) G01N 33/53 (2006.01) G01N 33/561 (2006.01) G01N 37/00 (2006.01) G06F 17/30 (2006.01) G06N 3/00 (2006.01) C12Q 1/68 (2006.01) G01N 27/447 (2006.01)

Patent

CA 2486431

A method for identifying a quantitative trait loci for a complex trait that is exhibited by a plurality of organisms in a population. The population is divided into a plurality of sub-populations using a classification scheme. Depending on what is known about the population, either a supervised or unsupervised classification is used. The classification scheme is derived from a plurality of cellular constituent measurements obtained from each organism in the population. For each sub-population in the plurality of sub- populations, a quantitative genetic analysis is performed on the sub- population in order to identify one or more quantitative trait loci for the complex trait.

L'invention concerne un procédé d'identification de loci de traits quantitatifs pour un trait complexe qui est présenté par une pluralité d'organismes dans une population. La population est divisée en une pluralité de sous-populations au moyen d'un schéma de classification. Selon les informations connues sur la population, on peut faire appel à une classification supervisée ou non supervisée. Le schéma de classification est dérivé d'une pluralité de mesures de constituants cellulaires obtenues de chaque organisme dans la population. Pour chaque sous-population dans la pluralité de sous-populations, une analyse génétique quantitative est effectuée sur la sous-population de façon à identifier un ou plusieurs loci de trait quantitatif pour le trait complexe.

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