Concentrate of a factor viii:c-containing von willebrand...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/745 (2006.01) A61K 38/36 (2006.01) A61K 38/37 (2006.01) A61P 7/04 (2006.01) C07K 1/30 (2006.01) C07K 14/755 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2443463

The invention relates to a concentrate and a process for producing a factor VIII:C-containing von Willebrand factor by fractional precipitation from a liquid comprising factor VIII:C and von Willebrand factor, resulting in an increased content of high molecular weight multimers of von Willebrand factor and a ratio of the vWF:RCoF activity to vWF:Ag of greater than 1.

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