Concentrates of coagulation factors ii, vii, ix and x,...

C - Chemistry – Metallurgy – 12 – Q

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150/11, 150/15.3

C12Q 1/56 (2006.01) C12N 9/64 (2006.01) G01N 33/52 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1330302

ABSTRACT OF THE DISCLOSURE: Concentrates of coagulation factors II, VII, IX and X may be prepared by selective sorption on an equilibrated carrier based on hydroxyethylmethacrylate or hydroxyethylacrylate with bound diethylaminoethyl-groups followed by selective desorption. The concentrates of coagulation factors II and X can be used for the determination of coagulation factor VII and in a laboratory method for detection or determina- tion of the extent of mammalian inflammatory diseases.

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