Condensation derivatives of thiocolchicine and baccatin as...

Details Condensation derivatives of thiocolchicine and baccatin as... Condensation derivatives of thiocolchicine and baccatin as...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01) A61K 31/337 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2403168

N-Deacetyl-thiocolchicine and 10-deacetyl-baccatine III derivatives of formula (I) wherein R and n have the meanings specified in the disclosure, are valuable antitumoral drugs.

La présente invention concerne les dérivés de N-déacétyl-thiocolchicine et 10-déacétyl-baccatine III de formule (I), dans laquelle R et n sont tels que décrits dans le descriptif; ces dérivés constituant de précieux médicaments antitumoraux.

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