C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/210, 260/239
C07D 243/38 (2006.01) A61K 31/55 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)
Patent
CA 1320198
Condensed Diazepinones Abstract The invention relates to condensed diazepinones of formula I Image (I) wherein Image represents one of the groups Image (S) (T) (U) (V) (W) Xl and x2 each represents a methine group or, when Image represents a group (S),(U) or (W), Xl and X2 may alternatively be nitrogen atoms, A represents a C16 alkylene group, R1 and R2 represent lower alkyl groups or R1 and R2 together with the intervening nitrogen atom also represent a saturated 4- to 7-membered heteroaliphatic ring, R3 represents lower alkyl or hydrogen or chlorine, R4 and R10 each represents a hydrogen atom or a methyl group, R5 and R6 each represents a hydrogen, fluoride, chlorine or bromine . atom or a lower alkyl group, R7 represents a hydrogen or chlorine atom or a methyl group and R8 and R9 each represents a hydrogen atom or a lower alkyl group and R9 may also represent a halogen atom. These compounds are suitable for treating bradycardia and bradyarrhythmia.
601877
de Jonge Adriaan
Doods Henri
Eberlein Wolfgang
Engel Wolfhard
Mayer Norbert
de Jonge Adriaan
Doods Henri
Eberlein Wolfgang
Engel Wolfhard
Fetherstonhaugh & Co.
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