Condensed heterocyclic compounds, their production and use

Details Condensed heterocyclic compounds, their production and use Condensed heterocyclic compounds, their production and use

C - Chemistry, Metallurgy

07

D

C07D 491/22 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/675 (2006.01) A61K 31/69 (2006.01) C07D 495/22 (2006.01) C07F 5/04 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2087898

Condensed Heterocyclic Compounds, Their Production and Use ABSTRACT OF THE DISCLOSURE Novel compound represented by the formula: Image (I) wherein R' stands for an aliphatic hydrocarbon group substituted with a hydrophilic group; R0 stands for a lower alkyl group; R1 and R2 independently stand for a hydrogen atom or an optionally substituted lower hydrocarbon group; X1 and X2 independently stand for -O-, -S(O)?-(K denotes a whole number of 0 to 2), Image (R3 stands for a hydrogen atom or an optionally substituted lower hydrocarbon group) or an optionally substituted methylene group: i denotes a whole number of 1 to 3; and R1 and R2 may be different from each other at the repetition of the number i, or a salt thereof which has a topoisomerase I inhibition activity and is useful as an antitumor agents.

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