Condensed heterocyclic compounds, their production and use

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/04 (2006.01) A61K 38/04 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07K 7/06 (2006.01) C08G 69/48 (2006.01)

Patent

CA 2057635

ABSTRACT OF THE DISCLOSURE Condensed Heterocyclic Compounds, Their Production and Use A novel compound of the formula: Image wherein a ring A stands for an optionally substituted 5-membered ring; B stands for an optionally substituted divalent cyclic or chain group; either one of Q1 and Q2 stands for N and the other stands for N or CH; X stands for an amino group, hydroxyl group or mercapto group; Y stands for H, halogen atom or a group bonded through C, N, O or S; Z stands for a straight-chain divalent group having 2 to 5 atoms constituted of optionally substituted carbon atoms or constituted of optionally substituted carbon atoms and one optionally substituted hetero-atom; COOR1 and COOR2 independently stand for an optionally esterified carboxyl group; n denotes an integer of 2 to 6; and R1 may be different in each of n repeating units, or their salts and it is useful as a therapeutic drug for tumor in mammals.

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