Condensed heterocyclic compounds, their production and use

Details Condensed heterocyclic compounds, their production and use Condensed heterocyclic compounds, their production and use

C - Chemistry, Metallurgy

07

D

C07D 217/14 (2006.01) A61K 31/33 (2006.01) C07D 311/76 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 405/00 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 407/12 (2006.01) C07D 409/02 (2006.01) C07D 409/12 (2006.01) C07D 413/02 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/10 (2006.01) C07D 491/107 (2006.01) C07D 495/10 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2148047

The compound Image wherein ring A represents a benzene ring; Ar represents an aromatic group; R1 and R2 independently represent hydrogen, acyl or hydrocarbon group or R1 and R2 taken together with the adjacent nitrogen atom represent a nitrogen-containing heterocyclic group; m represents an integer of 1 to 6; n represents an integer of 2 to 3; = ? represents a single bond or a double bond; X stands for -O- or -NR - in which R3 represents hydrogen, acyl or hydrocarbon group where ?is a single bond or =N- where ? is a double bond has excellent GnRH receptor antagonizing activity, calcium antagonizing and monoamine-uptake inhibiting activities and and value as a prophylactic/therapeutic drug for sex hormone-dependent diseases and for central diseases.

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