Condensed heterocyclic glutamic acid derivatives as...

Details Condensed heterocyclic glutamic acid derivatives as... Condensed heterocyclic glutamic acid derivatives as...

C - Chemistry, Metallurgy

07

D

C07D 513/04 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 487/04 (2006.01) C07D 517/04 (2006.01)

Patent

CA 2154668

Novel compounds of formula (I) are found to inhibit the enzyme glycinamide ribonucleotide formyl transferase (GARFT). A novel method of preparing such compounds is also disclosed, as well as methods and compositions for employing the compounds as antiproliferative agents.

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