Condensed-hexacyclic compounds and a process therefor

Details Condensed-hexacyclic compounds and a process therefor Condensed-hexacyclic compounds and a process therefor

C - Chemistry, Metallurgy

07

D

C07D 491/22 (2006.01) A61K 31/4745 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2173671

Disclosed are a process for the preparation of a compound represented by the formula (1), which com- prises treating a compound represented by the formula (2) with methanesulfonic acid and then subjecting the thus-treated compound to recrystallization; and Com- pound (1) so obtained. Image This Compound (1) is free of hygroscopicity, excellent in filterability and solubility and easy in handling. Furthermore, according to the preparation process of the present invention, an unnecessary isomer can be converted into the target one and separation of the target isomer can be conducted easily.

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