Condensed purine derivatives

Details Condensed purine derivatives Condensed purine derivatives

C - Chemistry, Metallurgy

07

D

167/218, 260/242

C07D 487/14 (2006.01) A61K 31/52 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2028235

There are disclosed condensed purine derivatives represented by formula: Image wherein Image represents Image , Image or Image in which R3 represents hydrogen, lower alkyl or benzyl; each of X1 and X independently represents hydrogen, lower alkyl, aralkyl or phenyl; and n is an integer of 0 or 1; R1 represents hydrogen, lower alkyl, alicyclic alkyl, noradamantan-3-yl, dicyclopropylmethyl or styryl; and R represents hydrogen, lower alkyl or alicyclic alkyl; or a pharmaceutically acceptable salt thereof. The derivatives and pharmaceutically acceptable salts are useful as diuretics, renal protecting agents, antiallergic agents and hypotensives.

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