Condensed purine derivatives as a1 adenosine receptor...

Details Condensed purine derivatives as a1 adenosine receptor... Condensed purine derivatives as a1 adenosine receptor...

C - Chemistry, Metallurgy

07

D

C07D 487/14 (2006.01) A61K 31/505 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2430508

Compounds of Formula I and II are disclosed as antagonists of subtype A1 adenosine receptors. These compounds are useful for treatment of various diseases and disorders, including systemic hypertension, renal failure, diabetes, asthma, an edematous condition, congestive heart failure, and renal dysfunction.

L'invention concerne des composés représentés par les formules I et II servant d'antagonistes des récepteurs d'adénosine de sous-type A1. Ces composés sont utilisés dans le traitement de diverses maladies et troubles, y compris l'hypertension systémique, l'insuffisance rénale, le diabète, l'asthme, un état oedémateux, l'insuffisance cardiaque congestive, et un dysfonctionnement rénal.FORMULE I FORMULE II

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