C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/14 (2006.01) A61K 31/4985 (2006.01) A61P 9/00 (2006.01) A61P 15/00 (2006.01) C07D 471/04 (2006.01) C07D 471/14 (2006.01) C07D 471/22 (2006.01) C07D 487/14 (2006.01) C07D 491/14 (2006.01)
Patent
CA 2413510
Compounds of the general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents. In particular, the invention relates to compounds that are potent and selective inhibitors of cyclic guanosine 3', 5'-monophosphate specific phosphodiesterase (cGMP- specific PDE), in particular PDE5.
La présente invention concerne des composés représentés par la formule structurelle (I) et l'utilisation de ces composés, de leurs sels et de leurs solvates, comme agents thérapeutiques.
Orme Mark W.
Sawyer Jason Scott
Schultze Lisa M.
Lilly Icos Llc
Ridout & Maybee Llp
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