Condensed pyridoindole derivatives

Details Condensed pyridoindole derivatives Condensed pyridoindole derivatives

C - Chemistry, Metallurgy

07

D

C07D 498/14 (2006.01) A61K 31/437 (2006.01) A61P 9/00 (2006.01) A61P 15/10 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 263/00 (2006.01) C07D 277/00 (2006.01) C07D 291/00 (2006.01) C07D 471/14 (2006.01) C07D 513/14 (2006.01) C07D 515/14 (2006.01)

Patent

CA 2423312

Compounds of general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents._In particular, the invention relates to compounds that are potent and selective inhibitors of cyclic guanosine 3', 5' -monophosphate specific phosphodiesterase (cGMP-specific PDE), in particular PDE5, and have utilisty in a variety of therapeutic areas wherein such inhibition is considered beneficial, including the treatment of cardiovascular disorders and erectile dysfunction.

Cette invention, qui a trait à des composés correspondant à la formule générale de structure (I), concerne également l'utilisation de ces composés, de leurs sels et de leurs solvates en tant qu'agents thérapeutiques.

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