Condensed thiadiazole derivative, method of its production,...

C - Chemistry – Metallurgy – 07 – D

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C07D 513/04 (2006.01) A61K 31/425 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 519/00 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2092390

Abstract of the disclosure (1) a compound represented by the following formula(I): Image (I) wherein R represents a hydrocarbon group or heterocyclic group which may be substituted for; the ring A represents a pyridine ring having a substituent or a thiazole ring which may be substituted for; or a pharmaceutically acceptable salt thereof, and a method of its production, and (2) an endothelin receptor antagonist, an cathepsin B inhibitor or a bone resorption suppressor comprising as an active ingredient a compound represented by the following formula (I'): Image (I') wherein R has the same definition as in term (1); the ring A' represents a pyridine ring or thiazole ring which may be substituted for; or a pharmaceutically acceptable salt thereof.

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