Condii toxoplasma p30 expression cassette

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/30 (2006.01) A61K 31/70 (2006.01) A61K 35/56 (2006.01) A61K 35/66 (2006.01) A61K 38/16 (2006.01) A61K 39/012 (2006.01) A61K 48/00 (2006.01) C07K 14/45 (2006.01) C07K 16/20 (2006.01) C12N 15/79 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2194873

Expression cassette for the production and secretion of a Toxoplasma gondii P30 protein in a non-mammal cell, a vector, a cell comprising it and the antibodies capable of being produced. The invention also concerns a method for the preparation of the P30 protein, a method for the detection of anti- toxoplasma antibodies or the P30 protein, the corresponding reagents and a pharmaceutical composition for the treatment or prevention of a Toxoplasma gondii infection.

La présente invention concerne une cassette d'expression pour la production et la sécrétion d'une protéine P30 de Toxoplasma gondii dans une cellule non-mammifère, un vecteur, une cellule la comprenant et les anticorps pouvant être générés. Elle a également trait à un procédé de préparation de la protéine P30, un procédé de détection d'anticorps anti-toxoplasme ou de la protéine P30, les réactifs correspondants ainsi qu'à une composition pharmaceutique pour le traitement ou la prévention d'une infection à Toxoplasma gondii.

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