C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) C12N 15/10 (2006.01)
Patent
CA 2380395
The invention provides method for producing nucleic acid ligands that generate a signal, or cause a decrease in the level of a signal, in the presence of a target molecule or an environmental stimulus. The methods of the instant invention are collectively termed Conditional SELEX. The nucleic acid ligands of the instant invention are useful in any application where it is desirable to measure the concentration of a target molecule or detect and quantitate an environmental stimulus.
L'invention concerne un procédé de production de ligands d'acide nucléique, qui génèrent un signal ou induisent un baisse de niveau du signal, en présence d'une molécule cible ou d'un stimulus environnemental. Les procédés de l'invention sont désignés collectivement par le terme SELEX Conditionnel. Les ligands d'acide nucléique de l'invention sont utiles dans toute application, quelle qu'elle soit, dans laquelle il est souhaitable de mesurer la concentration d'une molécule cible ou de détecter et quantifier un stimulus environnemental.
Gold Larry
Smith Jonathan Drew
Mbm Intellectual Property Law Llp
Somalogic Inc.
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