Conducting polymer nanotube actuators for precisely...

A - Human Necessities – 61 – N

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A61N 1/30 (2006.01) A61K 47/34 (2006.01) A61K 50/00 (2006.01) A61M 31/00 (2006.01)

Patent

CA 2694431

Drug delivery devices, their manufacture, and their use comprising electrocontractile nanotubes that can be used for precise controlled bioactive substance release for example, medical, veterinary, pharmaceutical compounds and growth factors. The conducting polymer nanotubes significantly decrease the impedance and increase the charge capacity of recording electrode sites on microfabricated electrode devices. Bioactive substances released from the nanotubes can be controlled in a desired fashion by controlled electrical stimulation of the nanotubes.

La présente invention concerne des dispositifs d'administration de médicaments, leur fabrication, et leur utilisation, lesdits dispositifs comprenant des nanotubes électriquement contractiles qui peuvent être utilisés pour une libération précise contrôlée de substance biologiquement active, par exemple des composés médicaux, vétérinaires, pharmaceutiques et des facteurs de croissance. Les nanotubes à base de polymères conducteurs diminuent de manière significative l'impédance et augmentent la capacité de charge de sites d'électrodes d'enregistrement sur les dispositifs d'électrodes microfabriquées. Les substances biologiquement actives libérées à partir des nanotubes peuvent être contrôlées d'une manière souhaitée par une stimulation électrique contrôlée des nanotubes.

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