Conformationally constrained amino acid compounds having...

Details Conformationally constrained amino acid compounds having... Conformationally constrained amino acid compounds having...

C - Chemistry, Metallurgy

07

D

C07D 209/54 (2006.01) A61K 31/195 (2006.01) A61K 31/40 (2006.01) C07C 229/28 (2006.01) C07D 205/12 (2006.01) C07D 209/44 (2006.01) C07D 209/46 (2006.01) C07D 209/96 (2006.01)

Patent

CA 2322558

Novel substituted amino acids of formulae (I) to (VIII) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, and neuropathological disorders. Processes for the preparation and intermediates useful in the preparation are also disclosed.

L'invention concerne de nouveaux acides aminés substitués selon les formules (I) à (VIII). Ces acides présentent une grande utilité comme agents dans le traitement de l'épilepsie, des crises de lipothymie, d'hypokinésie, de troubles craniens, de troubles neurodégénératifs, de dépression, d'anxiété, de panique, de douleurs et de troubles neuropathologiques. L'invention traite de procédés pour la préparation de ces acides et d'intermédiaires utiles dans leur préparation.

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