Conformationally constrained carboxylic acid derivatives...

C - Chemistry – Metallurgy – 07 – C

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C07C 59/72 (2006.01) A61K 31/192 (2006.01) A61K 31/435 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) C07D 213/64 (2006.01)

Patent

CA 2716352

The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I or the general formula III: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.

La présente invention concerne des composés utiles pour traiter par exemple des troubles du métabolisme chez un sujet. Ces composés ont la formule générale I ou la formule générale III dont les définitions des variables sont fournies ici. La présente invention concerne également des compositions qui comprennent des composés qui entrent dans la préparation de médicaments, ainsi que des procédés pour utiliser ces composés et pour traiter des troubles du métabolisme comme, par exemple, un diabète de type II.

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