Conformationally constrained lh-rh analogues, their uses and...

Details Conformationally constrained lh-rh analogues, their uses and... Conformationally constrained lh-rh analogues, their uses and...

C - Chemistry, Metallurgy

07

K

C07K 7/23 (2006.01) A61K 38/09 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2270158

The invention relates to LH-RH peptide analogues with excellent affinity for LH-RH receptors, of the formula: V-W-X-SPL-Y-Pro-Z where V, W, X, SPL, Y and Z are as defined in the specification. The invention also relates to the uses of said peptide analogues and to the pharmaceutical compositions containing them.

L'invention porte sur des analogues du peptide LH-RH de la formule: V-W-X-SPL-Y-Pro-Z, lesquels présentent une excellente affinité pour les récepteurs de la lulibérine. Dans ladite formule, V, W, X, SPL, Y et Z sont tels que définis dans la description. L'invention porte également sur les utilisations desdits analogues du peptide et sur les compositions pharmaceutiques contenant ceux-ci.

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