Congenic animal models of non-insulin dependent diabetes...

Details Congenic animal models of non-insulin dependent diabetes... Congenic animal models of non-insulin dependent diabetes...

C - Chemistry, Metallurgy

12

N

C12N 15/17 (2006.01) A61K 38/28 (2006.01) C07K 14/62 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2389852

Congenic animals and animal populations having type II diabetes-associated phenotypes are described. Insulin degradation polypeptides having amino acid substitutions linked to a type II diabetes-associated phenotypes also are described.

L'invention concerne des animaux congéniques et des populations animales présentant des phénotypes associés au diabète de type II. Elle se rapporte également à des polypeptides de dégradation de l'insuline présentant des substitutions d'acide aminé liées à des phénotypes associés au diabète de type II.

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