C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/44 (2006.01) A61K 31/4015 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01)
Patent
CA 2430827
The invention relates to novel active agents (coniosetin and coniosetin derivatives) of formula I, which are produced by the micro-organism Coniochaeta ellipsoidea Udagawa (DSM 13856) during fermentation, R, R2, R3, R4, R5, X, X2, X3 and X4 having the meanings given. The invention also relates to chemical derivatives of coniosetin, to a method for producing them and to the use of the same as medicaments.
La présente invention concerne de nouveaux principes actifs (coniosétine et dérivés de coniosétine) de la formule I, qui sont formés par les micro-organismes <i>Coniochaeta ellipsoidea</i> Udagawa (DSM 13856) pendant la fermentation, R, R¿2?, R¿3?, R¿4?, R¿5?, X, X¿2?, X¿3? et X¿4? ayant la signification donnée. L'invention concerne également des dérivés chimiques de la coniosétine, leur procédé de production et leur utilisation comme médicaments.
Fassy Florence
Knauf Martin
Markus Astrid
Raynal-Wetzel Mark-Cecile
Toti Luigi
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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