A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 38/17 (2006.01) A61K 47/42 (2006.01) A61K 48/00 (2006.01) C12N 15/62 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2379346
The present invention relates to conjugates for mediating a cell-specific, compartment-specific or membrane-specific transport of active substances. The invention also relates to methods of preparing these conjugates as well as their use. The conjugates comprise: - a transport mediator for the cell membrane, - a cell-specific, compartment-specific or membrane- specific address protein or peptide, and - an active substance to be transported.
La présente invention concerne des conjugués destinés à la mise en oeuvre d'un transport de substances actives spécifique selon les cellules, compartiments ou membranes. L'invention concerne également des procédés de fabrication de ces conjugués ainsi que leur utilisation. Ces conjugués comprennent un agent de transport pour la membrane cellulaire, une protéine ou un peptide d'adressage spécifique selon les cellules, compartiments ou membranes, et une substance active devant être transportée.
Braun Klaus
Debus Jurgen
Friedrich Eckart
Peschke Peter
Pipkorn Rudiger
Deutsches Krebsforschungszentrum Stiftung Des Offentilichen Rech
Moffat & Co.
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