A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/09 (2006.01) A61K 39/116 (2006.01)
Patent
CA 2648593
The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, a multivalent Streptococcus pneumoniae immunogenic composition is provided with various (for instance 9 or more) conjugated capsular saccharides from different S. pneumoniae serotypes, wherein the composition comprises conjugated capsular saccharide 18C which is less than 80, 70, 60, 50, 40, 30, 20, 15 or 10 % O- Acetylated.
La présente invention concerne le domaine des vaccins à saccharide capsulaire conjugué de pneumocoque. Spécifiquement, une composition immunogénique plurivalente de Streptococcus pneumoniae est obtenue avec plusieurs (par exemple 9 ou plus) saccharides capsulaires conjugués provenant de différents sérotypes deS. pneumoniae, ladite composition comprenant le saccharide capsulaire 18C conjugué qui est O-acétylé à moins de 80, 70, 60, 50, 40, 30, 20, 15 ou 10 %.
Biemans Ralph Leon
Denoel Philippe
Poolman Jan
Prieels Jean Paul
Glaxosmithkline Biologicals S.a.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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